TyloVet Injection

Description

Injectable solution containing tylosin 200mg/mL, as tylosin base

Pack Sizes

Available in 100mL and 250mL multidose vials.

Action

Tylosin is a broad spectrum antibiotic active against Gram+ve bacteria, including staphylococci, streptococci, Corynebacteria spp. and Erysipelothrix rhusiopathiae (insidiosa), and Gram-ve bacteria such as Campylobacter coli , as well as selected spirochaetes. It is also active against Mycoplasma spp. of both birds and mammals, including cattle, sheep, goats and pigs.
Because of its spectrum of activity, its lipid solubility and weakly basic reaction (which favours accumulation in inflamed tissues), along with its uptake by macrophages, tylosin is indicated for the treatment of mastitis, metritis, pneumonia and footrot (necrotic pododermatitis).

Indication

Cattle: Treatment and control of acute mastitis (caused by Streptococcus uberis, S.dysgalactiae, S.agalactiae, Staphylococcus aureus, coagulase negative Staphylococci), metritis caused by Trueperella pyogenes, respiratory infections caused by Pasteurella multocida, foot-rot (necrotic pododermatitis) and calf diphtheria caused by Fusobacterium necrophorum.
Pigs: Treatment and control of ileitis associated with Lawsonia intracellularis, swine erysipelas caused by Erysipelothrix rhusiopathiae, pneumonia caused by Mycoplasma hyopneumoniae and M. hyorhinis, and arthritis due to Mycoplasma hyosynoviae and M. hyorhinis.
Sheep and Goats: Treatment of the early stages of peracute and acute contagious agalactia caused by Mycoplasma agalactiae and caprine pleuropneumonia caused by Mycoplasma mycoides var capri (M.capri).

Dosage

Administer by IM injection in cattle, pigs, sheep and goats or by slow IV injection in cattle only. Rapid IV injection may cause ataxia, dyspnoea and increased salivation. Give intramuscular injections into the anterior half of the neck. Alternate the injection site when giving repeated daily doses. Administer doses over 15mL at different sites.
Cattle (including calves): 5 - 10mg/kg (2.5 - 5mL/100kg) LW daily. Do not administer for more than 5 days.
Pigs: 5 - 10mg/kg (0.25 - 0.5mL/10kg) LW daily. Do not administer for more than 3 days.
Sheep and Goats: 10mg/kg (0.5mL/10kg) LW daily. Do not administer for more than 5 days.

Withholding times

Meat: Animals producing meat and offal for human consumption must not be sold for slaughter either
during treatment or within 21 days of the last treatment.
Milk: Milk intended for sale for human consumption or manufacture for human consumption must be
discarded during treatment and for 72 hours following the last treatment.

Special Precautions

Tylosin is an antibiotic in the macrolide family, and is considered critically important to human and animal health. Indiscriminate use of this antibiotic can contribute to the development of antibiotic resistance, and it should not be used as a first line treatment. The use of this antibiotic should be reserved for the treatment of conditions that respond poorly to other classes of antibiotic following culture and sensitivity testing, or in cases where other treatments have been clinically determined to be ineffective.

Use of this antibiotic should be limited to the minimum period needed to meet the clinical objective. Clinical response should be monitored during treatment, and choice of therapy reviewed if clinical signs of disease persist, increase, or relapse.

Other

Store below 25°C, protected from light. Discard unused content 28 days after opening.
ACVM Registration Number A10807. Restricted Veterinary Medicine. Available only under Veterinary Authorisation. 

Video Links

Dairy NZ's Healthy Udder video presented by AgriHealth's Dr Steve Cranefield 

Associated Documents

TyloVet Injection NZ Label TyloVet Injection SDS