Kolibin Neo Vaccine

Description

Each vaccination dose contains inactivated bovine rotavirus, bovine coronavirus, and 3 serovars of enteropathic strains of E. coli K99
Contains adjuvant and thiomersal (0.01% w/v) as a preservative

Pack Sizes

Available in 100mL (50 dose) and 250mL (125 dose) plastic bottles.

Action

Vaccination of dams with Kolibin Neo boosts the level of antibodies in the colostrum. Colostral transfer of antibodies provides the newborn calf with passive immunity against gastrointestinal diseases caused by rotavirus, coronavirus and enteropathogenic E. coli strains.

Indication

For active immunisation of pregnant heifers and cows to provide calves with passive immunity against gastrointestinal diseases caused by rotavirus, coronavirus and enteropathogenic E. coli strains. When calves consume colostrum and milk from vaccinated cows during the first four weeks of life, these antibodies reduce the incidence and severity of diarrhoea caused by rotavirus, coronavirus and E. coli (K99) and reduce virus shedding by infected calves.

Dosage

Warm the vaccine to between 15°C - 25°C and shake the content of the vial before use. Administer to cattle. Dose is 2 mL by intramuscular or subcutaneous injection.
Previously unvaccinated heifers or cows should receive two doses 3 weeks apart, with the second dose given 12 - 2 weeks prior to calving. Annually revaccinate with a single dose of Kolibin Neo 12 - 2 weeks prior to calving.
Alternatively, Kolibin Neo can be given as an annual booster vaccination to animals vaccinated with Rotavec Corona (A08312) or ScourGuard 4(K) (A10057) in the previous year.
The recommended site is the anterior third of the neck. To minimise the potential for swelling at the site of injection, ensure vaccination is by deep intramuscular injection or directed subcutaneous. Do not vaccinate at sites other than the recommended site.
Feeding calves with Colostrum: In order to ensure the effective prevention of gastroenteric disease in calves, calves must receive adequate colostrum from vaccinated cows or heifers. Newborn calves should receive at least 2L of this colostrum, preferably from the first milking and within 6 hours. Calves should continue to receive colostrum and milk from vaccinated cows and heifers for at least 2 - 4 weeks after birth at the rate of 2.5 - 4 L per day, to ensure maximal protection.
Optimum protection of calves against infection is achieved if all cows and heifers in the herd are vaccinated, annually.
As for any vaccine, very high levels of challenge have the potential to overwhelm vaccinal immunity. Best practice calf rearing, with attention to hygiene and facilities is recommended to minimise disease challenge, and optimise the effect of vaccination.

Withholding times

Nil.

Special Precautions

Vaccinate healthy animals only. A protective immune response may not be established if animals are immunocompromised in any way.

Other

Store in a refrigerator at 2°C – 8°C. Do not freeze. Protect from light. A partially used pack can be kept for use for up to 28 days.
ACVM Registration Number A11242. Restricted Veterinary Medicine. Available only under Veterinary Authorisation.

Associated Documents

Kolibin Neo NZ Label Kolibin Neo SDS Kolibin Neo Brochure Kolibin Neo Farmer Fact Sheet Optimal Calf Rearing Guide Tech Bulletin V4 - Dynamics of Antibodies to Kolibin Neo in Colostrum and Milk Tech Bulletin V5 - Clinical Field Trial to assess efficacy of Kolibin Neo Tech Bulletin V9 - Efficacy of Kolibin Neo under challenge model conditions Tech Bulletin V10 - Vaccinating for calf scours Tech Bulletin V11 - Kolibin Neo Field Study Tech Bulletin V12 - Kolibin Neo IM vs SQ Tech Bulletin V13 - Understanding rotavirus genotypes Tech Bulletin V15 - Latest Research on Colostrum Preservation