Eimeriavax 4m

Description

Live attenuated coccidiosis vaccine for oral administration containing viable sporulated oocysts from proprietary strains of Eimeria acervulina, E. maxima, E. necatrix and E. tenella suitable for use in laying, breeding and broiler chickens

Pack Size

PACK CONTENTS:
10 plastic bottles of 1,000 doses each in 25 mL of buffer solution; 10,000 chick doses per pack

STORAGE INSTRUCTIONS:
Product should be stored between 2°C and 8°C (refrigerated) away from sunlight. Do not freeze. Product should be used by the expiry date. Use all product within 6 hours of opening and dilution.

Action

EIMERIAVAX 4m contains live, attenuated and precocious, highly immunogenic, coccidiostat-sensitive strains of Eimeria acervulina, E. maxima, E. necatrix and E. tenella.  Vaccination of young chicks stimulates immunity to and minimises the risk of coccidiosis infections throughout the production cycle.

Indication

Live oocyst preparation to aid in the control of the four major species of Eimeria that cause coccidiosis in breeders, broilers and layer chickens.

Administration and dose

Birds from day-old can be vaccinated with EIMERIAVAX 4m. With individual bird administration, it is essential for each bird to receive a full dose. It is recommended that all birds be vaccinated prior to 18 weeks of age. The most appropriate age to vaccinate may be determined from knowledge of the challenge conditions applicable to the flocks concerned. The effect of EIMERIAVAX 4m vaccination during lay has not been assessed.

SPRAY METHOD OF ADMINISTRATION:
EIMERIAVAX 4m has been demonstrated effective when administered using a hatchery spray apparatus that delivers 24 mL of diluted vaccine per box of 100 day-old chicks, i.e. 0.24 mL per chick. Please note the following points:
The vaccine is to be diluted in water or phosphate buffered saline. Blue food grade dye should be added to the diluent prior to spraying to encourage uptake of the vaccine by preening. If using a spray apparatus that delivers 24 mL per 100-chick box, one bottle of 1000 dose EIMERIAVAX 4m is diluted to a total volume of 240 mL.

• Open the vaccine bottle when required by peeling back the foil cap and removing the rubberbung.
• Ensure the diluted vaccine is regularly agitated during the spray applications to ensure vaccine oocysts do not settle.
• The spray unit should deliver an even mist with the added blue dye evident. Ensure mist covers all chicks.
• After spraying, leave the chicks in a light place to allow preening and vaccine ingestion.
• Use all vaccine within 6 hours of dilution.

Please contact AgriHealth NZ Ltd if further information regarding specific spray units is required.

Contraindications

This product is contraindicated for vaccinating unhealthy birds.

Withholding Period

Nil

Special Precautions

Do not use in-feed or water anticoccidial medications at or soon after the time of vaccination. Avoid administration of sulfa drugs immediately following vaccination with EIMERIAVAX 4m as this will delay oocyst output and impair immune response.
Avoid vaccinating with EIMERIAVAX 4m unless birds are protected from exposure to litter from the previous batch for up to 21 days post-vaccination.
Do not use EIMERIAVAX 4m as a diluent for other medications or treatments.
Avoid using in birds in lay.

BIRD MANAGEMENT AFTER ADMINISTRATION:
Continued exposure to oocysts shed in faeces is essential for the development of an effective immune response.
Birds can be vaccinated from day-old.
Concurrent anticoccidial medication is never recommended.
If depression associated with vaccination is noted, light intensity should be increased and/or extended and extra feed provided.
Monitor birds carefully for 4 weeks post-vaccination. Some lesions can be expected. Lesions can be associated with an immune response and should not be used as the sole criterion for assessing efficacy.
Investigate all suspect coccidiosis lesions as this vaccine does not protect against Eimeria species that are not represented in the vaccine. Monitor gross lesion scores for 4 weeks post-vaccination.

Duration of immunity: Continuing exposure to oocysts in the environment is essential and provides ongoing stimulus to the immune system. Under these exposure conditions, a protective immune response beyond 18 weeks of age may be experienced. When birds are removed from the source of vaccine oocysts, such as when they are transferred between facilities, immunity may wane due to reduced exposure to cycling oocysts. As a result, birds may subsequently become susceptible to field infections from Eimeria species represented in the vaccine.

Safety Information

USER SAFETY INFORMATION:

Accidental contact of EIMIERIAVAX 4m with eyes or mouth may cause irritation. Eyes should be rinsed immediately and medical advice sought. The mouth should be rinsed two or three times with a mouth gargle.
Additional information is available on the product Safety Data Sheet above.

FIRST AID:
If poisoning occurs, contact a Doctor.

DISPOSAL:
Discard unused vaccine and empty vaccine bottles into a disinfectant solution (e.g. chlorine based bleach). Dispose of any such inactivated, unused vaccine and empty containers by wrapping in paper and putting in garbage.
In cases of spillage, soak up the liquid with an absorbent sponge or cloth and incinerate. Treat the surface with a disinfectant solution (e.g. chlorine-based bleach).

Other Information

CAUTION:
The capability of this vaccine to produce satisfactory results depends upon many factors including, but not limited to, conditions of storage and handling by the user, administration of the vaccine, health and responsiveness of individual birds and degree of field exposure. Therefore, directions for use should be followed carefully.

EIMERIAVAX 4m is manufactured by Bioproperties Pty Ltd., Australia for Huvepharma, Europe.
ACVM Registration Number A11638

ASSOCIATED DOCUMENTS

Eimeriavax 4 NZ label Eimeriavax 4 SDS Eimeriavax 4 brochure Eimerivax 4 - Administration at hatchery Eimeriavax 4 eye drop Eimeriavax 4 -Administration spray on birds