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BioBos IBR Marker Vaccine

Contains inactivated bovine herpesvirus type-1 (BoHV-1) for cattle

Features

Monovalent IBR marker vaccine for cattle
Innovative technology allowing DIVA (Differentiating Infected from Vaccinated Animals) principle
Award winning European manufacturer
Modern tissue-friendly and efficacious adjuvant
Non-GM inactivated vaccine
Available in 50 dose (100ml) plastic bottles

Benefits

Excellent efficacy against new infections, resulting in substantially reduced viral shedding
Latency of bovine herpesvirus maintained in previously infected cattle
Specific ELISA test can be used to differentiate field infected from vaccinated animals
High quality modern vaccine from Europe
Highly effective antibody and cell-mediated immune response
Operator and animal friendly
Convenient for NZ herd use

Further Info Associated Documents

Description

Each 2mL vaccination dose contains inactivated bovine herpesvirus type 1 (BoHV-1)
Also contains adjuvant and thiomersal

Pack Sizes

Available in 100mL (50 dose) plastic bottles

Action

In general, a viral particle of bovine herpesvirus type 1 (BoHV-1) consists of several dozen glycoproteins. Six of these glycoproteins are considered immunodominant (i.e. the level of antibodies produced against these six glycoproteins is significantly higher than against other glycoproteins). These are glycoproteins B, C, D, E, H, and I. Biobos IBR Marker Vaccine contains a vaccine strain of BoHV-1 that is missing the gE expression gene. The term "marker" vaccine used in the literature in connection with IBR means a "gE negative vaccine", i.e. a vaccine containing BoHV-1 with a missing gene for glycoprotein E (gE).

Biobos IBR Marker Vaccine enables differentiation of vaccinated animals from infected animals. In combination with diagnostic testing, cattle vaccinated with Biobos IBR Marker Vaccine (gE-) can be differentiated from cattle that have been naturally infected (gE+).

Indication

For active immunisation of cattle to reduce intensity and duration of clinical symptoms caused by infection with bovine herpesvirus type 1 (IBR) virus and to reduce excretion of the field virus.

Dosage

CATTLE: Administer 2 mL, by intramuscular injection into the anterior half of the neck.
Initial vaccination should be given at three months of age or older to avoid interference by maternal antibodies. Administer booster vaccination three weeks after first (sensitiser) vaccination.
Onset of immunity is 3 weeks after booster vaccination.
Booster vaccination may be repeated at six monthly intervals.

Withholding times

Nil

Special Precautions

Vaccinate healthy animals only. Safe for use in pregnant and lactating cattle.

Other

Store in a refrigerator (2°C – 8°C). Do not freeze. Protect from light.
A partially used pack should be discarded after 28 days.
ACVM Registration Number A11239. Restricted Veterinary Medicine. Available only under Veterinary Authorisation.

Associated Documents