Biobos IBR Marker Vaccine

Biobos IBR Marker Vaccine

Contains inactivated bovine herpesvirus type-1 (BoHV-1) for cattle


  • Monovalent IBR marker vaccine for cattle
  • Innovative technology allowing DIVA (Differentiating Infected from Vaccinated Animals) principle
  • Award winning European manufacturer
  • Modern tissue-friendly and efficacious adjuvant
  • Non-GM inactivated vaccine
  • Available in 50 dose (100ml) plastic bottles


  • Excellent efficacy against new infections, resulting in substantially reduced viral shedding
  • Latency of bovine herpesvirus maintained in previously infected cattle

  • Specific ELISA test can be used to differentiate field infected from vaccinated animals
  • High quality modern vaccine from Europe
  • Highly effective antibody and cell-mediated immune response
  • Operator and animal friendly
  • Convenient for NZ herd use


Each 2mL vaccination dose contains inactivated bovine herpesvirus type 1 (BoHV-1)
Also contains adjuvant and thiomersal

Pack Sizes

Available in 100mL (50 dose) plastic bottles


In general, a viral particle of bovine herpesvirus type 1 (BoHV-1) consists of several dozen glycoproteins. Six of these glycoproteins are considered immunodominant (i.e. the level of antibodies produced against these six glycoproteins is significantly higher than against other glycoproteins). These are glycoproteins B, C, D, E, H, and I. Biobos IBR Marker Vaccine contains a vaccine strain of BoHV-1 that is missing the gE expression gene. The term "marker" vaccine used in the literature in connection with IBR means a "gE negative vaccine", i.e. a vaccine containing BoHV-1 with a missing gene for glycoprotein E (gE).

Biobos IBR Marker Vaccine enables differentiation of vaccinated animals from infected animals. In combination with diagnostic testing, cattle vaccinated with Biobos IBR Marker Vaccine (gE-) can be differentiated from cattle that have been naturally infected (gE+).


For active immunisation of cattle to reduce intensity and duration of clinical symptoms caused by infection with bovine herpesvirus type 1 (IBR) virus and to reduce excretion of the field virus.


CATTLE: Administer 2 mL, by intramuscular injection into the anterior half of the neck.
Initial vaccination should be given at three months of age or older to avoid interference by maternal antibodies. Administer booster vaccination three weeks after first (sensitiser) vaccination.
Onset of immunity is 3 weeks after booster vaccination.
Booster vaccination may be repeated at six monthly intervals.

Withholding times


Special Precautions

Vaccinate healthy animals only. Safe for use in pregnant and lactating cattle.


Store in a refrigerator (2°C – 8°C). Do not freeze. Protect from light.
A partially used pack should be discarded after 28 days.
Restricted Veterinary Medicine, ACVM Registration Number A11239